Allergens

Hives can develop when the body reacts to an allergen. When an allergic reaction occurs, the body releases a protein called histamine. Next, tiny blood vessels called capillaries leak fluid. This fluid accumulates in the skin and causes inflammation and a rash. As fluid accumulates under the skin, small bumps form.

The reaction can occur if a person consumes something or touches something that they are allergic to. This is known as “contact urticaria.”

If acute hives results from an allergic reaction, the cause may be:

  • a medication, such as:
    • some antibiotics
    • some nonsteroidal anti-inflammatory drugs, or NSAIDs, such as aspirin
    • angiotensin converting enzyme inhibitors, which are drugs for high blood pressure
  • nuts, eggs, seafood, or another food allergen
  • latex
  • kiwi, banana, chestnuts, or mango, in people with a latex allergy
  • some plants, including nettles, poison ivy, and poison oak
  • additives in some foods, cosmetics, and other products

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