Category: Hoffmann Bromamide Reaction

1. Preparation of aniline  2. Preparation of methylamine  Hoffmann Bromamide Degradation Reaction Mechanism  Hoffmann bromamide reaction mechanism can be explained in the following steps –  Step 1: In this step primary amide reacts with sodium hydroxide. Hydroxide ion(anion) of NaOH attacks on a group of primary amides which results in deprotonation of primary amides and…

As the name of the reaction suggests, Hoffmann’s bromamide degradation reaction was given by August Wilhelm Von Hoffmann. It is also known as the Hoffmann Rearrangement Reaction. This reaction is used to form primary amines. Let’s understand the name of the reaction first so that it will be easy for you to remember the reaction. …